Article Sidebar

Download
PDF
Statistic
Read Counter : 1034 Download : 608

Downloads

Download data is not yet available.

Main Article Content

Abstract

Blumea balsamifera (L.) DC. or Sembung is a flowering plant belonging to the genus Blumea of the family Asteraceae. Many pharmacological activities of this plant show potential in human therapy. In this study, an investigation was conducted on the ethanolic extract of B. balsamifera collected from a geothermal area known as Ie-Jue, in Aceh Province, Indonesia. The results showed that the ethanolic extract of B. balsamifera contained secondary metabolites of flavonoids and tannins. Chemical constituents of ethanolic extracts B. balsamifera further analysis using gas chromatography-mass spectrometry (GC-MS) show that active compounds from this plant was Proximadiol (C15H28O2) with relative area 41.76%. This research underscores the compelling potential of the Ie-Jue geothermal area as a promising reservoir of flora owing to the plant's adaptability to geothermal extremities.

Keywords

Sembung Proximadiol GC-MS Mount Seulawah Agam Borneol

Article Details

License

Copyright (c) 2023 Nur Balqis Maulydia, Khairan Khairan, Trina Ekawati Tallei, Ethiene Castellucci Estevam, Mohsina Patwekar, Fazlin Mohd Fauzi, Rinaldi Idroes

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite
Maulydia, N. B., Khairan, K., Tallei, T. E., Estevam, E. C., Patwekar, M., Mohd Fauzi, F., & Idroes, R. (2023). GC-MS Analysis Reveals Unique Chemical Composition of Blumea balsamifera (L.) DC in Ie-Jue Geothermal Area. Grimsa Journal of Science Engineering and Technology, 1(1), 9–16. https://doi.org/10.61975/gjset.v1i1.6
Download Citation
Endnote/Zotero/Mendeley (RIS)
BibTeX

References

  1. Abubakar A, Yusuf H, Syukri M, Nasution R, Yusuf M, Idroes R. Heavy metals contamination in geothermal medicinal plant extract (Chromolaena odorata Linn). Global Journal of Environmental Science and Management 2023;9:995–1004. https://doi.org/10.22035/gjesm.2023.04.22.
  2. Maulydia NB, Idroes R, Khairan K, Tallei TE, Mohd Fauzi F. Ecotoxicological insight of phytochemicals, toxicological informatics, and heavy metal concentration in Tridax procumbens L. in geothermal areas. Global Journal of Environmental Science and Management 2024;10:369–84. https://doi.org/10.22034/gjesm.2024.01.23.
  3. Idroes GM, Syahnur S, Majid MSA, Idroes R, Kusumo F, Hardi I. Unveiling the Carbon Footprint: Biomass vs. Geothermal Energy in Indonesia. Ekonomikalia Journal of Economics 2023;1:10–8. https://doi.org/10.60084/eje.v1i1.47.
  4. Idroes R, Yusuf M, Saiful S, Alatas M, Subhan S, Lala A, et al. Geochemistry Exploration and Geothermometry Application in the North Zone of Seulawah Agam, Aceh Besar District, Indonesia. Energies 2019;12:4442. https://doi.org/10.3390/en12234442.
  5. Bahri RA, Noviandy TR, Suhendra R, Idroes GM, Yanis M, Yandri E, et al. Utilization of Drone with Thermal Camera in Mapping Digital Elevation Model for Ie Seu’um Geothermal Manifestation Exploration Security. Leuser Journal of Environmental Studies 2023;1:25–33. https://doi.org/10.60084/ljes.v1i1.40.
  6. Idroes R, Yusuf M, Alatas M, Subhan, Lala A, Muhammad, et al. Geochemistry of Sulphate spring in the Ie Jue geothermal areas at Aceh Besar district, Indonesia. IOP Conference Series: Materials Science and Engineering 2019;523. https://doi.org/10.1088/1757-899X/523/1/012012.
  7. Aprianto A, Maulana A, Noviandy TR, Lala A, Yusuf M, Marwan M, et al. Exploring Geothermal Manifestations in Ie Jue , Indonesia : Enhancing Safety with Unmanned Aerial Vehicle. Leuser Journal of Environmental Studies 2023;1:47–54. https://doi.org/10.60084/ljes.v1i2.75.
  8. Maulydia NB, Khairan K, Noviandy TR. Prediction of Pharmacokinetic Parameters from Ethanolic Extract Mane Leaves (Vitex pinnata L.) in Geothermal Manifestation of Seulawah Agam Ie-Seu’um, Aceh. Malacca Pharmaceutics 2023;1:16–21. https://doi.org/10.60084/mp.v1i1.33.
  9. Nuraskin C, Marlina, Idroes R, Soraya C, Djufri. Identification of secondary metabolite of laban leaf extract (Vitex pinnata l) from geothermal areas and non-geothermal of agam mountains in Aceh Besar, Aceh province, Indonesia. Rasayan Journal of Chemistry 2020;13:18–23. https://doi.org/10.31788/RJC.2020.1315434.
  10. Ningsih DS, Celik I, Abas AH, Bachtiar BM, Kemala P, Idroes GM, et al. A Review of the Ethno-dentistry Activities of Calotropis gigantea. Malacca Pharmaceutics 2023;1:8–15.
  11. Idroes R, Khairan, Fakri F. Skrining Aktivitas Tumbuhan yang berpotensi sebagai bahan antimikroba di kawasan ie Jue (upflow geotermal Zone) Aceh besar. Banda Aceh: Unsyiah Press; 2017.
  12. Fakri F, Harahap SP, Muhni A, Khairan K, Hewindati YT, Idroes GM. Antimicrobial Properties of Medicinal Plants in the Lower Area of Ie Seu-um Geothermal Outflow, Indonesia. Malacca Pharmaceutics 2023;1:55–61. https://doi.org/10.60084/mp.v1i2.44.
  13. Imelda E, Khairan K, Lubis RR, Kemala P, Zulfiani U, Rahayu S, et al. Anticataract activity of ethanolic extract from Hippobroma longiflora (L.) G.Don leaves: Ex vivo investigation. Journal of Pharmacy & Pharmacognosy Research 2023;11:833–40. https://doi.org/10.56499/jppres23.1691_11.5.833.
  14. Rachmawati R, Idroes R, Suhartono E, Maulydia NB, Darusman D. In Silico and In Vitro Analysis of Tacca Tubers (Tacca leontopetaloides) from Banyak Island, Aceh Singkil Regency, Indonesia, as Antihypercholesterolemia Agents. Molecules 2022;27. https://doi.org/10.3390/molecules27238605.
  15. Abas AH, Tallei TE, Idroes R, Fatimawali F. Ficus minahassae (Teijsm. & de Vriese) Miq.: A Fig Full of Health Benefits from North Sulawesi, Indonesia: A Mini Review. Malacca Pharmaceutics 2023;1:1–7. https://doi.org/https://doi.org/10.60084/mp.v1i1.24.
  16. Khairan K, Arini M, Idroes R, Awang K, Jacob C. Antibacterial Activity of n-Hexane Dragon’s Blood Resin Extract (Daemonorops draco wild Blume) from Bener Meriah, Aceh Province, Indonesia. Malacca Pharmaceutics 2023;1:22–9. https://doi.org/https://doi.org/10.60084/mp.v1i1.29.
  17. Dolongtelide JI, Fatimawali F, Tallei TE, Suoth EJ, Simbala HEI, Antasionasti I, et al. In Vitro Antioxidant Activity of Chrysanthemum indicum Flowers Extract and Its Fraction. Malacca Pharmaceutics 2023;1:43–7. https://doi.org/10.60084/mp.v1i2.26.
  18. Idroes R, Khairan K, Fakri F. Screening of Potential Plant Activities as Antimicrobial Materials in the Ie Jue Area (Upflow Geothermal Zone) Aceh Besar. Banda Aceh: Syiah Kuala Universiti Press; 2017.
  19. Pang Y, Wang D, Fan Z, Chen X, Yu F, Hu X, et al. Blumea balsamifera- A phytochemical and pharmacological review. Molecules 2014;19:9453–77. https://doi.org/10.3390/molecules19079453.
  20. Widhiantara IG, Jawi IM. Phytochemical composition and health properties of Sembung plant (Blumea balsamifera): A review. Veterinary World 2021;14:1185–96. https://doi.org/www.doi.org/10.14202/vetworld.2021.1185-1196.
  21. Wang J, He H, Zhou Z, Bai L, She X, He L, et al. Chemical constituents and bioactivities of Blumea balsamifera (Sembung): a systematic review. Food Science and Technology (Brazil) 2023;43. https://doi.org/10.1590/fst.132322.
  22. Chu SS, Du SS, Liu ZL. Fumigant Compounds from Essential Oil of Chinese Blumea balsamifera Leaves againts the Maize Weevil (Sitophilus zeamais). Journal of Chemistry 2012;2013.
  23. Shirota O, Oribello JM, Sekita S, Satake M. Sesquiterpenes from Blumea balsamifera. Journal of Natural Products 2011;74:470–6. https://doi.org/10.1021/np100646n.
  24. Harborne JB. Phytochemical Methods: A Guide to Modern Techniques of Plant Analysis. 1987.
  25. Kim S, Chen J, Cheng T, Gindulyte A, He J, He S, et al. PubChem 2023 update. Nucleic Acids Research 2023;51:D1373–80. https://doi.org/10.1093/nar/gkac956.
  26. Filimonov DA, Lagunin AA, Gloriozova TA, Rudik A V., Druzhilovskii DS, Pogodin P V., et al. Prediction of the biological activity spectra of organic compounds using the pass online web resource. Chemistry of Heterocyclic Compounds 2014;50:444–57. https://doi.org/10.1007/s10593-014-1496-1.
  27. Rolnik A, Olas B. The plants of the asteraceae family as agents in the protection of human health. International Journal of Molecular Sciences 2021;22:1–10. https://doi.org/10.3390/ijms22063009.
  28. Masyudi, Hanafiah M, Rinidar, Usman S, Marlina. Phytochemical screening and GC-MS analysis of bioactive compounds of Blumea balsamifera leaf extracts from South Aceh, Indonesia. Biodiversitas 2022;23:1346–54. https://doi.org/10.13057/biodiv/d230319.
  29. El-Askary HI, Meselhy MR, Galal AM. Sesquiterpenes from Cymbopogon proximus. Molecules 2003;8:670–7. https://doi.org/10.3390/80900670.
  30. Poirier D. Inhibitors of 17B-Hydroxysteroid Dehydrogenases. Current Medicinal Chemistry 2012;10:453–77. https://doi.org/10.2174/0929867033368222.